Product Details:
Payment & Shipping Terms:
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| Cas:: | 486459-03-4 | Form:: | Whtie Or Light Yellow Powder |
|---|---|---|---|
| Price:: | Negotiation | Payment Terms:: | Western Union, MoneyGram,Bitocoin |
| Usage:: | Research Chemicals | Packaging De Tails:: | Aluminium Foil Bags And Boxes; As Your Demand |
| Formula:: | C17H25NO | Other Name:: | U49900 U50860 |
| Email:: | Aimee@hiersunchem.com | Skype:: | Aimeechem-168 |
| High Light: | opioid research chemicals legal,strongest research chemical |
||
U 44770 Research Chemical Intermediates , Safe Opioid Research Chemicals Legal
U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selectiveagonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models.
U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
contact details:
aimee@hierunchem.com
skype: aimeechem-168
Analogues:
| Product name | U-47700 |
| CAS | 82657-23-6 |
| IUPAC name | 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide |
| Formula | C16H22Cl2N2O |
| Molecular weight | 329.27g/mol |
| Compound purity | 99% |
| Appearance | white powder |
| Application | For lab research |
| Storage | Keep in cool and dry place |
| Package | aluminium alloy bag or according to requirement |
| Place of origin | Hebei |
| Type of shipping | EMS, TNT, FEDEX, DHL, UPS |
| Payment terms | T/T or Western Union or Money Gram or Bitcoin |
| Delivery time | Within 1-3 days |
| MOQ | 10g |
| Production capacity | 500kg/month |
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