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Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity

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Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity

China Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity supplier
Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity supplier Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity supplier Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity supplier Ethylphenidate EPH Research Chemical CAS No. 57413-43-1 White Powder 90% Purity supplier

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CAS No.:: 57413-43-1 Payment Terms:: T/T,WU,Paypal,Money Gram
Appearance:: White Powder Email:: Aimee@hiersunchem.com
Skype:: Aimeechem-168 Means Of Transport:: Ocean,Air;EMS,FedEx,DHL
Usage:: For Research
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Products: Ethylphenidate ethylphenidate EP ep white powder 90% purity

Model No.:140703-51-1

Production Capacity:20 Kilogram/Kilograms per D...

Delivery Date:within 3 days

CAS No.:140703-51-1

Pure:99%

Delivery time:In stock ,within 24 hours

Skype: aimeechem-168

Min order:10g

Means of Transport:Land, Ocean, Air

Packing:Aluminum Foil Bag

Brand Name:HX

Purity:99%

Application:lab research

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Examorelin (INN) (developmental code names EP-23905, MF-6003), also known as hexarelin, is a potent,synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue which was developed by Mediolanum Farmaceutici.[3][4][5][6][7] It is a hexapeptide with the amino acid sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 which was derived from GHRP-6. These GH-releasing peptides have no sequence similarity to ghrelin, but mimic ghrelin by acting as agonists at the ghrelin receptor.[5][6]

Examorelin substantially and dose-dependently increases plasma levels of growth hormone (GH) in animals and humans.[2] In addition, similarly to pralmorelin (GHRP-2) and GHRP-6, it slightly and dose-dependently stimulates the release of prolactin, adrenocorticotropic hormone (ACTH), and cortisol in humans.[2][8] There are conflicting reports on the ability of examorelin to elevate insulin-like growth factor 1 (IGF-1) andinsulin-like growth factor-binding protein 1 (IGFBP-1) levels in humans, with some studies finding no increase and others finding a slight yet statistically significant increase.[2][9][10][11] Examorelin does not affect plasma levels of glucose, luteinizing hormone (LH), follicle-stimulating hormone (FSH), or thyroid-stimulating hormone (TSH) in humans.[2]

Examorelin releases more GH than does growth hormone-releasing hormone (GHRH) in humans,[8][12] and produces synergistic effects on GH release in combination with GHRH, resulting in "massive" increases in plasma GH levels even with only low doses of examorelin.[13][14][15] Pre-administration of GH blunts the GH-releasing effect of examorelin, while, in contrast, fully abolishing the effect of GHRH.[14][16] Pre-treatment with IGF-1 also blunts the GH-elevating effect of examorelin.[17] Testosterone, testosterone enanthate, andethinylestradiol, though not oxandrolone, have been found to significantly potentiate the GH-releasing effects of examorelin in humans.[18][19] In accordance, likely due to increases in sex steroid levels,puberty has also been found to significantly augment the GH-elevating actions of examorelin in humans.[20]

A partial and reversible tolerance to the GH-releasing effects of examorelin occurs in humans with long-term administration (50–75% decrease in efficacy over the course of weeks to months).[21][22]

Examorelin reached phase II clinical trials for the treatment of growth hormone deficiency and congestive heart failure but did not complete development and was never marketed.

 

Name

Replacement

Ethylone

Dibutylone

Ethylone

BK-EDBP

a-pvp

4C-PVP

a-pvp

TH-PVP

a-pvp

4f-php

4-cmc

2-NMC

4-cmc

4-CEC

3-cmc

4-CPRC

EP

Dimethylphenidate(DP)

ab-chminaca

mab-chminaca (MABC)

JWH/5F-PB22/FUB-PB22

5F-PCN

AH-7921

U-47700

PB-22/ AM2201

FDU-PB-22

AB-FUBINACA

ADB-FUBINACA

SDB-006

5F-sdb005

AKB-48

FUB-AKB48

 

Dibutylone

BK-EBDP

4-MPD

Fub-amb

2NMC

4-CEC

4BMC

BB-22

5F-AEB

Eg2201

MPHP

4cprc

Mmb-chminaca

mab-chminaca

4-EMC

TH-PVP

FUB-AMB

4clpvp

5F-PCN

Etizolam

4C-PVP

4F-PHP

U-47700

FDU-PB-22

ADB-FUBINACA

5F-sdb005

NM-2201

FUB-AKB48

PV10 powder

 

 

 

 

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