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EP ethylphenidate white powder 90% purity best quality favourable price

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EP ethylphenidate white powder 90% purity best quality favourable price

China EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier
EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier EP   ethylphenidate    white powder  90% purity  best quality  favourable price supplier

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CAS: 140703-51-1 Email: Nannie@hiersunchem.com
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Model No.:140703-51-1
Production Capacity:20 Kilogram/Kilograms per D...
Delivery Date:within 3 days
CAS No.:140703-51-1
Pure:99%
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Skype:nannie(at)hiersunchem(dot)com
Min order:10g
Means of Transport:Land, Ocean, Air
Packing:Aluminum Foil Bag
Brand Name:HS
Purity:99%
Application:lab research
Payment term:Western Union ,Money Gram, Bitcoin
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Examorelin (INN) (developmental code names EP-23905, MF-6003), also known as hexarelin, is a potent,synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue which was developed by Mediolanum Farmaceutici.[3][4][5][6][7] It is a hexapeptide with the amino acid sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 which was derived from GHRP-6. These GH-releasing peptides have no sequence similarity to ghrelin, but mimic ghrelin by acting as agonists at the ghrelin receptor.[5][6]

Examorelin substantially and dose-dependently increases plasma levels of growth hormone (GH) in animals and humans.[2] In addition, similarly to pralmorelin (GHRP-2) and GHRP-6, it slightly and dose-dependently stimulates the release of prolactin, adrenocorticotropic hormone (ACTH), and cortisol in humans.[2][8] There are conflicting reports on the ability of examorelin to elevate insulin-like growth factor 1 (IGF-1) andinsulin-like growth factor-binding protein 1 (IGFBP-1) levels in humans, with some studies finding no increase and others finding a slight yet statistically significant increase.[2][9][10][11] Examorelin does not affect plasma levels of glucose, luteinizing hormone (LH), follicle-stimulating hormone (FSH), or thyroid-stimulating hormone (TSH) in humans.[2]

Examorelin releases more GH than does growth hormone-releasing hormone (GHRH) in humans,[8][12] and produces synergistic effects on GH release in combination with GHRH, resulting in "massive" increases in plasma GH levels even with only low doses of examorelin.[13][14][15] Pre-administration of GH blunts the GH-releasing effect of examorelin, while, in contrast, fully abolishing the effect of GHRH.[14][16] Pre-treatment with IGF-1 also blunts the GH-elevating effect of examorelin.[17] Testosterone, testosterone enanthate, andethinylestradiol, though not oxandrolone, have been found to significantly potentiate the GH-releasing effects of examorelin in humans.[18][19] In accordance, likely due to increases in sex steroid levels,puberty has also been found to significantly augment the GH-elevating actions of examorelin in humans.[20]

A partial and reversible tolerance to the GH-releasing effects of examorelin occurs in humans with long-term administration (50–75% decrease in efficacy over the course of weeks to months).[21][22]

Examorelin reached phase II clinical trials for the treatment of growth hormone deficiency and congestive heart failure but did not complete development and was never marketed.

EP   ethylphenidate    white powder  90% purity  best quality  favourable price
 
Name Replacement
Ethylone Dibutylone
Ethylone BK-EDBP
a-pvp 4C-PVP
a-pvp TH-PVP
a-pvp 4f-php
4-cmc 2-NMC
4-cmc 4-CEC
3-cmc 4-CPRC
EP Dimethylphenidate(DP)
ab-chminaca mab-chminaca (MABC)
JWH/5F-PB22/FUB-PB22 5F-PCN
AH-7921 U-47700
PB-22/ AM2201 FDU-PB-22
AB-FUBINACA ADB-FUBINACA
SDB-006 5F-sdb005
AKB-48 FUB-AKB48

 

Dibutylone BK-EBDP
4-MPD Fub-amb
2NMC 4-CEC
4BMC BB-22
5F-AEB Eg2201
MPHP 4cprc
Mmb-chminaca mab-chminaca
4-EMC TH-PVP
FUB-AMB 4clpvp
5F-PCN Etizolam
4C-PVP 4F-PHP
U-47700 FDU-PB-22
ADB-FUBINACA 5F-sdb005
NM-2201 FUB-AKB48
PV10 powder  

 

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